CKD-506: A novel HDAC6-selective inhibitor that exerts therapeutic effects in a rodent model of multiple sclerosis

Abstract Despite advances in therapeutic strategies for multiple sclerosis (MS), the therapy options remain limited with various adverse effects. Here, the therapeutic potential of CKD-506, a novel HDAC6-selective inhibitor, against MS was evaluated in mice with myelin oligodendrocyte glycoprotein35...

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Autores principales: Daekwon Bae, Ji-Young Lee, Nina Ha, Jinsol Park, Jiyeon Baek, Donghyeon Suh, Hee Seon Lim, Soo Min Ko, Taehee Kim, Da Som Jeong, Woo-chan Son
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5f77b10b118742ed8e9fb83f53cbdc9f
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