Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines.
M. tuberculosis (MTB) species-specific antigenic determinants of the human T cell response are important for immunodiagnosis and vaccination. As hypoxia is a stimulus in chronic tuberculosis infection, we analyzed transcriptional profiles of MTB subject to 168 hours of hypoxia to test the hypothesis...
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Auteurs principaux: | , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2010
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Accès en ligne: | https://doaj.org/article/5f7c112149f143e6abf37c61a78902fa |
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