Tau Cleavage Contributes to Cognitive Dysfunction in Strepto-Zotocin-Induced Sporadic Alzheimer’s Disease (sAD) Mouse Model

Tau Cleavage Contributes to Cognitive Dysfunction in Strepto-Zotocin-Induced Sporadic Alzheimer’s Disease (sAD) Mouse Model

Tau cleavage plays a crucial role in the onset and progression of Alzheimer’s Disease (AD), a widespread neurodegenerative disease whose incidence is expected to increase in the next years. While genetic and familial forms of AD (fAD) occurring early in life represent less than 1%, the sporadic and...

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Détails bibliographiques
Auteurs principaux: Valentina Latina, Giacomo Giacovazzo, Pietro Calissano, Anna Atlante, Federico La Regina, Francesca Malerba, Marco Dell’Aquila, Egidio Stigliano, Bijorn Omar Balzamino, Alessandra Micera, Roberto Coccurello, Giuseppina Amadoro
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
tau cleavage
non-transgenic Alzheimer’s Disease mouse model
streptozotocin (STZ)
immunotherapy
cognitive/memory impairment
neuroinflammation
Biology (General)
QH301-705.5
Chemistry
QD1-999
Accès en ligne:https://doaj.org/article/5f991db7a1c14822a963b16909db6ad5
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https://doaj.org/article/5f991db7a1c14822a963b16909db6ad5

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