Influenza A virus segments five and six can harbor artificial introns allowing expanded coding capacity.
Influenza A viruses encode their genomes across eight, negative sense RNA segments. The six largest segments produce mRNA transcripts that do not generally splice; however, the two smallest segments are actively spliced to produce the essential viral proteins NEP and M2. Thus, viral utilization of R...
Saved in:
Main Authors: | Heather M Froggatt, Kaitlyn N Burke, Ryan R Chaparian, Hector A Miranda, Xinyu Zhu, Benjamin S Chambers, Nicholas S Heaton |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/5f9db5129dae43e99d5e7c7d6e8b2e01 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Identification of introns harboring functional sequence elements through positional conservation
by: Michal Chorev, et al.
Published: (2017) -
An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites
by: Tooba Abbassi-Daloii, et al.
Published: (2017) -
Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats
by: Magdalena Derbis, et al.
Published: (2021) -
Expanding the genetic code of Mus musculus
by: Songmi Han, et al.
Published: (2017) -
Bypassing the EPR effect with a nanomedicine harboring a sustained-release function allows better tumor control
by: Shen YA, et al.
Published: (2015)