Synergistic sequence contributions bias glycation outcomes

Advanced glycation end-products (AGEs), such as methylglyoxal-derived hydroimidazolone isomer (MGH-1), are associated with disease and age-related disorders, and occur spontaneously, so it is unclear why specific protein sites become modified with specific AGEs. Here, the authors use a combinatorial...

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Autores principales: Joseph M. McEwen, Sasha Fraser, Alexxandra L. Sosa Guir, Jaydev Dave, Rebecca A. Scheck
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5fba806714964ba4b997f252adebc342
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