Redesigning metabolism based on orthogonality principles

Growth-coupled designs for chemical production are limited by native metabolic networks’ optimality for growth. Here, the authors introduce pathway orthogonality as a measure of the independence of biomass and chemical production pathways, identify metabolic valves that allow substrate utilization t...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Aditya Vikram Pandit, Shyam Srinivasan, Radhakrishnan Mahadevan
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/5fcc9a50e6a74fc7a3de77700c2ed0d3
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!