Binding of Host Cell Surface Protein Disulfide Isomerase by <named-content content-type="genus-species">Anaplasma phagocytophilum</named-content> Asp14 Enables Pathogen Infection
ABSTRACT Diverse intracellular pathogens rely on eukaryotic cell surface disulfide reductases to invade host cells. Pharmacologic inhibition of these enzymes is cytotoxic, making it impractical for treatment. Identifying and mechanistically dissecting microbial proteins that co-opt surface reductase...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2020
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| Accès en ligne: | https://doaj.org/article/5fcfb0454aa64878b57f1f16d651b6f8 |
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