Binding of Host Cell Surface Protein Disulfide Isomerase by <named-content content-type="genus-species">Anaplasma phagocytophilum</named-content> Asp14 Enables Pathogen Infection

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Binding of Host Cell Surface Protein Disulfide Isomerase by <named-content content-type="genus-species">Anaplasma phagocytophilum</named-content> Asp14 Enables Pathogen Infection

ABSTRACT Diverse intracellular pathogens rely on eukaryotic cell surface disulfide reductases to invade host cells. Pharmacologic inhibition of these enzymes is cytotoxic, making it impractical for treatment. Identifying and mechanistically dissecting microbial proteins that co-opt surface reductase...

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Autores principales:	Ryan S. Green, Waheeda A. Naimi, Lee D. Oliver, Nathaniel O’Bier, Jaehyung Cho, Daniel H. Conrad, Rebecca K. Martin, Richard T. Marconi, Jason A. Carlyon
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2020
Materias:	adhesin Anaplasma phagocytophilum obligate intracellular bacteria protein disulfide isomerase host-pathogen interactions Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/5fcfb0454aa64878b57f1f16d651b6f8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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