Prolactin-Induced Adaptation in Glucose Homeostasis in Mouse Pregnancy Is Mediated by the Pancreas and Not in the Forebrain
Adaptive changes in glucose homeostasis during pregnancy require proliferation of insulin-secreting beta-cells in the pancreas, together with increased sensitivity for glucose-stimulated insulin secretion. Increased concentrations of maternal prolactin/placental lactogen contribute to these changes,...
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Main Authors: | Zin Khant Aung, Ilona C. Kokay, David R. Grattan, Sharon R. Ladyman |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Online Access: | https://doaj.org/article/5fd72de4ea9e4462a13638d7b474802e |
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