Flavonoid fraction of Bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-κB inhibition in THP-1 monocytes.

Plant polyphenols exert anti-inflammatory activity through both anti-oxidant effects and modulation of pivotal pro-inflammatory genes. Recently, Citrus bergamia has been studied as a natural source of bioactive molecules with antioxidant activity, but few studies have focused on molecular mechanisms...

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Autores principales: Roberto Risitano, Monica Currò, Santa Cirmi, Nadia Ferlazzo, Pietro Campiglia, Daniela Caccamo, Riccardo Ientile, Michele Navarra
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/5ff25008a6fa4456b0704eebed1964af
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