Flavonoid fraction of Bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-κB inhibition in THP-1 monocytes.
Plant polyphenols exert anti-inflammatory activity through both anti-oxidant effects and modulation of pivotal pro-inflammatory genes. Recently, Citrus bergamia has been studied as a natural source of bioactive molecules with antioxidant activity, but few studies have focused on molecular mechanisms...
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Autores principales: | Roberto Risitano, Monica Currò, Santa Cirmi, Nadia Ferlazzo, Pietro Campiglia, Daniela Caccamo, Riccardo Ientile, Michele Navarra |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/5ff25008a6fa4456b0704eebed1964af |
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