Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
Osteocytes are the master regulatory cells within the skeleton. Here, the authors map the transcriptome of osteocytes from diverse skeletal sites, ages and between sexes and identify an osteocyte transcriptome signature associated with rare skeletal disorders and common complex skeletal diseases.
Guardado en:
Autores principales: | Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, Sindhu T. Mohanty, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Melita D. Irving, Ana Beleza-Meireles, Fernando Rivadeneira, Emma Duncan, J. Brent Richards, David J. Adams, Christopher J. Lelliott, Robert Brink, Tri Giang Phan, John A. Eisman, David M. Evans, Eleftheria Zeggini, Paul A. Baldock, J. H. Duncan Bassett, Graham R. Williams, Peter I. Croucher |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/60182d9a653b4b4d9d0b7b34378bcb3e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
In defence of the skeletal tier
por: R.J. Hayward
Publicado: (1988) -
Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength.
por: J H Duncan Bassett, et al.
Publicado: (2012) -
Accelerating functional gene discovery in osteoarthritis
por: Natalie C. Butterfield, et al.
Publicado: (2021) -
Publisher Correction: Accelerating functional gene discovery in osteoarthritis
por: Natalie C. Butterfield, et al.
Publicado: (2021) -
Perspectives on skeletal muscle stem cells
por: F. Relaix, et al.
Publicado: (2021)