Roles of Toll-like receptor 2/4, monoacylglycerol lipase, and cyclooxygenase in social defeat stress-induced prostaglandin E2 synthesis in the brain and their behavioral relevance
Abstract Inflammation in the brain and periphery has been associated with stress-related pathology of mental illness. We have shown that prostaglandin (PG) E2, an arachidonic acid-derived lipid mediator, and innate immune receptors Toll-like receptor (TLR) 2/4 are crucial for repeated stress-induced...
Guardado en:
Autores principales: | Xiang Nie, Shiho Kitaoka, Masakazu Shinohara, Akira Kakizuka, Shuh Narumiya, Tomoyuki Furuyashiki |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/60260c3f54e345d4b0c7bfbf9609e0e9 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression
por: Wei Xiang, et al.
Publicado: (2018) -
Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming
por: Naoto Muraoka, et al.
Publicado: (2019) -
Prostaglandin E2-EP3 axis in fine-tuning excessive skin inflammation by restricting dendritic cell functions.
por: Noriko Shiraishi, et al.
Publicado: (2013) -
Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis
por: Miao Yu, et al.
Publicado: (2017) -
Alpha-Synuclein, cyclooxygenase-2 and prostaglandins-EP2 receptors as neuroinflammatory biomarkers of autism spectrum disorders: Use of combined ROC curves to increase their diagnostic values
por: Afaf El-Ansary, et al.
Publicado: (2021)