Brain specific Lamellipodin knockout results in hyperactivity and increased anxiety of mice

Abstract Lamellipodin (Lpd) functions as an important signalling integrator downstream of growth factor and axon guidance receptors. Mechanistically, Lpd promotes actin polymerization by interacting with F-actin and the actin effectors Ena/VASP proteins and the SCAR/WAVE complex. Thereby, Lpd suppor...

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Autores principales: Cristian Bodo, Cathy Fernandes, Matthias Krause
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/602c36a7f5d1499a9eb0309abd188dfd
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