An HIV Vaccine Protective Allele in FCGR2C Associates With Increased Odds of Perinatal HIV Acquisition

In the Thai RV144 HIV-1 vaccine trial, a three-variant haplotype within the Fc gamma receptor 2C gene (FCGR2C) reduced the risk of HIV-1 acquisition. A follow-on trial, HVTN702, of a similar vaccine candidate found no efficacy in South Africa, where the predominant population is polymorphic for only...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Joy Ebonwu, Ria Lassaunière, Maria Paximadis, Mark Goosen, Renate Strehlau, Glenda E. Gray, Louise Kuhn, Caroline T. Tiemessen
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://doaj.org/article/606f17dc663147008740c3e9a01e0b5c
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!