A phase I study of the WT2725 dosing emulsion in patients with advanced malignancies

A phase I study of the WT2725 dosing emulsion in patients with advanced malignancies

Abstract WT2725 is a Wilms’ tumor gene 1 (WT1)-derived-oligopeptide vaccine designed to induce WT1-specific cytotoxic T-lymphocytes against WT1+ tumors in human leukocyte antigen (HLA)-A*0201+ and/or HLA-A*0206+ patients. Here, we report the results of a phase I study of WT2725. In this phase I, ope...

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Auteurs principaux: Siqing Fu, David E. Piccioni, Hongtao Liu, Rimas V. Lukas, Santosh Kesari, Dawit Aregawi, David S. Hong, Kenichiro Yamaguchi, Kate Whicher, Yi Zhang, Yu-Luan Chen, Nagaraju Poola, John Eddy, David Blum
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/60746137df784b578782dc3342f39baf
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Internet

https://doaj.org/article/60746137df784b578782dc3342f39baf

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