Monitoring Tacrolimus Concentrations in Whole Blood and Peripheral Blood Mononuclear Cells: Inter- and Intra-Patient Variability in a Cohort of Pediatric Patients

Monitoring Tacrolimus Concentrations in Whole Blood and Peripheral Blood Mononuclear Cells: Inter- and Intra-Patient Variability in a Cohort of Pediatric Patients

Tacrolimus (TAC) is a first-choice immunosuppressant for solid organ transplantation, characterized by high potential for drug-drug interactions, significant inter- and intra-patient variability, and narrow therapeutic index. Therapeutic drug monitoring (TDM) of TAC concentrations in whole blood (WB...

Full description

Saved in:
Bibliographic Details
Main Authors: Amedeo De Nicolò, Michele Pinon, Alice Palermiti, Antonello Nonnato, Alessandra Manca, Jacopo Mula, Silvia Catalano, Francesco Tandoi, Renato Romagnoli, Antonio D’Avolio, Pier Luigi Calvo
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
pharmacokinetics
immunosuppressant
pharmacology
pharmacokinetics-pharmacodynamics
transplantation
pharmacokinectics
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/60763e1cd80049c3a0135c3381f099e7
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/60763e1cd80049c3a0135c3381f099e7

Similar Items