Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis

Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis

Tripterygium wilfordii is a medical plant that can produce antitumor activity compound triptolide. Here, the authors assemble its genome and identify a cytochrome P450 that can catalyze oxidation of a methyl to the acid moiety of dehydroabietic acid in triptolide biosynthesis by integrating multi-om...

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Main Authors: Lichan Tu, Ping Su, Zhongren Zhang, Linhui Gao, Jiadian Wang, Tianyuan Hu, Jiawei Zhou, Yifeng Zhang, Yujun Zhao, Yuan Liu, Yadi Song, Yuru Tong, Yun Lu, Jian Yang, Cao Xu, Meirong Jia, Reuben J. Peters, Luqi Huang, Wei Gao
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
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Online Access:https://doaj.org/article/607c6a54fa534ef7bf5d30b6aa59d9b0
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