Depletion of white adipose tissue in cancer cachexia syndrome is associated with inflammatory signaling and disrupted circadian regulation.

Involuntary weight loss in patients with cancer is the hallmark of cancer cachexia. The etiology of cachexia is multifactorial involving loss of skeletal muscle and adipose tissue associated with high systemic levels of acute phase proteins and inflammatory cytokines. While muscle wasting overtly im...

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Auteurs principaux: Maria Tsoli, Martina Schweiger, Anne S Vanniasinghe, Arran Painter, Rudolf Zechner, Stephen Clarke, Graham Robertson
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
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Accès en ligne:https://doaj.org/article/608155561cad4b9abce08fe1f673149c
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