Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism

Abstract Major depressive disorder is a complex and common mental disease, for which the pathology has not been elucidated. The purpose of this study is to provide knowledge about the importance of mitochondrial dysfunction, dysregulated lipid metabolism and inflammation. Mitochondrial carnitine pal...

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Bibliographic Details
Main Authors: Anne Skøttrup Mørkholt, Ove Wiborg, Jette G. K. Nieland, Søren Nielsen, John Dirk Nieland
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/609d40b02d7a4b0797ff5bf08332f693
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