Improving formaldehyde consumption drives methanol assimilation in engineered E. coli

Engineering E. coli for metabolization of methanol to produce fuels and chemicals has not been fully achieved. Here, the authors combine metabolic engineering and chemical inhibition to improve methanol assimilation and distinguish the role of kinetics and thermodynamics under various culture condit...

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Auteurs principaux: Benjamin M. Woolston, Jason R. King, Michael Reiter, Bob Van Hove, Gregory Stephanopoulos
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/60acd311edfb421fb3ff1741090fb9a0
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