Frequency Domain Analysis of Fluctuations of mRNA and Protein Copy Numbers within a Cell Lineage: Theory and Experimental Validation

The stochasticity of gene expression is manifested in the fluctuations of messenger ribonucleic acid and protein copy numbers within a cell lineage over time. While data of this type can be obtained for many generations, most mathematical models are unsuitable to interpret such data since they assum...

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Bibliographic Details
Main Authors: Chen Jia, Ramon Grima
Format: article
Language:EN
Published: American Physical Society 2021
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Online Access:https://doaj.org/article/60f0ef6b28b34bc5b76b2422827e9f90
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