The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis

The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis

Dental calculus (DC) is a common deposit in periodontitis patients. We have previously shown that DC contains both microbial components and calcium phosphate crystals that induce an osteoclastogenic cytokine IL-1β via the NLRP3 inflammasome in macrophages. In this study, we examined the effects of c...

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Bibliographic Details
Main Authors: Megumi Mae, Mohammad Ibtehaz Alam, Yasunori Yamashita, Yukio Ozaki, Kanako Higuchi, S. M. Ziauddin, Jorge Luis Montenegro Raudales, Eiko Sakai, Takayuki Tsukuba, Atsutoshi Yoshimura
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
dental calculus
NLRP3 inflammasome
IL-1β
IL-18
osteoclast
Biology (General)
QH301-705.5
Chemistry
QD1-999
Online Access:https://doaj.org/article/60feb19b9f094e76a3b0fa941dedda72
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