Ectopic overexpression of Kir6.1 in the mouse heart impacts on the life expectancy

Abstract We recently reported the reduced ATP-sensitive potassium (KATP) channel activities in the transgenic mouse heart overexpressing the vascular type KATP channel pore-forming subunit (Kir6.1). Although dysfunction of cardiac KATP channel has been nominated as a cause of cardiomyopathy in human...

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Autores principales: Yasuhiro Watanabe, Takashi Kishimoto, Takashi Miki, Susumu Seino, Haruaki Nakaya, Akio Matsumoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6102e71ff39e47bda2eca019553263e0
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