α4/α9 Integrins Coordinate Epithelial Cell Migration Through Local Suppression of MAP Kinase Signaling Pathways

Adhesion of basal keratinocytes to the underlying extracellular matrix (ECM) plays a key role in the control of skin homeostasis and response to injury. Integrin receptors indirectly link the ECM to the cell cytoskeleton through large protein complexes called focal adhesions (FA). FA also function a...

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Auteurs principaux: Willow Hight-Warburton, Robert Felix, Andrew Burton, Hannah Maple, Magda S. Chegkazi, Roberto A. Steiner, John A. McGrath, Maddy Parsons
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://doaj.org/article/611a606d3f5e4468ae98a523635ec3f2
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