Prodrug polymeric micelles integrating cancer-associated fibroblasts deactivation and synergistic chemotherapy for gastric cancer

Abstract Background The prognosis of patients with advanced gastric cancer (GC) remains unsatisfactory owing to distant metastasis and resistance to concurrent systemic therapy. Cancer-associated fibroblasts (CAFs), as essential participators in the tumor microenvironment (TME), play a vital role in...

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Autores principales: Sheng Zheng, Jiafeng Wang, Ning Ding, Wenwen Chen, Hongda Chen, Meng Xue, Fei Chen, Jiaojiao Ni, Zhuo Wang, Zhenghua Lin, Haiping Jiang, Xiangrui Liu, Liangjing Wang
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/6145397e940c4526b0f8e554038217dc
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