PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure

Abstract Phosphatase and Tensin Homolog on chromosome Ten (PTEN) has emerged as a key protein that governs the response to kidney injury. Notably, renal adaptive repair is important for preventing acute kidney injury (AKI) to chronic kidney disease (CKD) transition. To test the role of PTEN in renal...

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Autores principales: Huizhen Wang, Yifan Wang, Xin Wang, Huimi Huang, Jingfu Bao, Wenhui Zhong, Aiqing Li
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/6190af0e0b1b481ba1da0d2451a0fe1f
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