Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons

Abstract Directed differentiation of human pluripotent stem cells (hPSCs) has enabled the generation of specific neuronal subtypes that approximate the intended primary mammalian cells on both the RNA and protein levels. These cells offer unique opportunities, including insights into mechanistic und...

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Autores principales: Daniel Moakley, Joan Koh, Joao D. Pereira, Daniel M. DuBreuil, Anna-Claire Devlin, Eugene Berezovski, Kevin Zhu, Brian J. Wainger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/61fc65bb89e1477982eb7445731e61fc
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