Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons

Abstract Directed differentiation of human pluripotent stem cells (hPSCs) has enabled the generation of specific neuronal subtypes that approximate the intended primary mammalian cells on both the RNA and protein levels. These cells offer unique opportunities, including insights into mechanistic und...

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Bibliographic Details
Main Authors: Daniel Moakley, Joan Koh, Joao D. Pereira, Daniel M. DuBreuil, Anna-Claire Devlin, Eugene Berezovski, Kevin Zhu, Brian J. Wainger
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/61fc65bb89e1477982eb7445731e61fc
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