Formal enantioconvergent substitution of alkyl halides via catalytic asymmetric photoredox radical coupling

Enantioselective substitution reactions of racemic alkyl halides are inherently limited by the specificity of their stereochemical course (SN1 or SN2). Here, the authors report a radical coupling strategy for the enantioselective aminoalkylation of α-bromoketones for modular, highly enantioselective...

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Autores principales: Jiangtao Li, Manman Kong, Baokun Qiao, Richmond Lee, Xiaowei Zhao, Zhiyong Jiang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/620596de496643598b0abf1cf4e483fc
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