Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice
Toxoplasma gondii virulence in wild-derived mice is restricted by Immunity-Related GTPases (IRG). Here, the authors show specific binding of the IRG tandem protein Irgb2-b1 with the virulence effector ROP5, and provide insights into how different ROP5 isoforms and IRG alleles shape virulence among T...
Enregistré dans:
Auteurs principaux: | Mateo Murillo-León, Urs B. Müller, Ines Zimmermann, Shishir Singh, Pia Widdershooven, Cláudia Campos, Catalina Alvarez, Stephanie Könen-Waisman, Nahleen Lukes, Zsolt Ruzsics, Jonathan C. Howard, Martin Schwemmle, Tobias Steinfeldt |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/6214204b6cb245a29596b1af94eefa25 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Author Correction: Molecular mechanism for the control of virulent Toxoplasma gondii infections in wild-derived mice
par: Mateo Murillo-León, et autres
Publié: (2019) -
Seroprevalence of <i>Toxoplasma gondii</i> in Pinnipeds under Human Care and in Wild Pinnipeds
par: Micaela Martins, et autres
Publié: (2021) -
Toxoplasma gondii infections are associated with costly boldness toward felids in a wild host
par: Eben Gering, et autres
Publié: (2021) -
Spatial distribution of anti-Toxoplasma gondii antibody-positive wild boars in Gifu Prefecture, Japan
par: Taizo Saito, et autres
Publié: (2021) -
A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice
par: Joanna Young, et autres
Publié: (2019)