Mood alterations in mouse models of Spinocerebellar Ataxia type 1

Abstract Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine-encoding CAG repeats in the Ataxin-1 (ATXN1) gene. SCA1 is characterized by progressive motor deficits, cognitive decline, and mood changes including anxiety and depression, w...

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Bibliographic Details
Main Authors: Melissa Asher, Juao-Guilherme Rosa, Marija Cvetanovic
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/621e832c225f4b51b497deb29caef4aa
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