Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations

Genome-wide maps of evolutionary constraint and large-scale compendia of epigenomic and transcription factor data provide complementary information for genome annotation. Here, the authors develop the Constrained Non-Exonic Predictor (CNEP) that enables better understanding of their relationship.

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Autores principales: Olivera Grujic, Tanya N. Phung, Soo Bin Kwon, Adriana Arneson, Yuju Lee, Kirk E. Lohmueller, Jason Ernst
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/627265ce26714edfacd642533c677bf1
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