Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations

Genome-wide maps of evolutionary constraint and large-scale compendia of epigenomic and transcription factor data provide complementary information for genome annotation. Here, the authors develop the Constrained Non-Exonic Predictor (CNEP) that enables better understanding of their relationship.

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Autores principales:	Olivera Grujic, Tanya N. Phung, Soo Bin Kwon, Adriana Arneson, Yuju Lee, Kirk E. Lohmueller, Jason Ernst
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/627265ce26714edfacd642533c677bf1
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spelling	oai:doaj.org-article:627265ce26714edfacd642533c677bf12021-12-02T17:31:41ZIdentification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations10.1038/s41467-020-19962-92041-1723https://doaj.org/article/627265ce26714edfacd642533c677bf12020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19962-9https://doaj.org/toc/2041-1723Genome-wide maps of evolutionary constraint and large-scale compendia of epigenomic and transcription factor data provide complementary information for genome annotation. Here, the authors develop the Constrained Non-Exonic Predictor (CNEP) that enables better understanding of their relationship.Olivera GrujicTanya N. PhungSoo Bin KwonAdriana ArnesonYuju LeeKirk E. LohmuellerJason ErnstNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Olivera Grujic Tanya N. Phung Soo Bin Kwon Adriana Arneson Yuju Lee Kirk E. Lohmueller Jason Ernst Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations
description	Genome-wide maps of evolutionary constraint and large-scale compendia of epigenomic and transcription factor data provide complementary information for genome annotation. Here, the authors develop the Constrained Non-Exonic Predictor (CNEP) that enables better understanding of their relationship.
format	article
author	Olivera Grujic Tanya N. Phung Soo Bin Kwon Adriana Arneson Yuju Lee Kirk E. Lohmueller Jason Ernst
author_facet	Olivera Grujic Tanya N. Phung Soo Bin Kwon Adriana Arneson Yuju Lee Kirk E. Lohmueller Jason Ernst
author_sort	Olivera Grujic
title	Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations
title_short	Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations
title_full	Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations
title_fullStr	Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations
title_full_unstemmed	Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations
title_sort	identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/627265ce26714edfacd642533c677bf1
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Identification and characterization of constrained non-exonic bases lacking predictive epigenomic and transcription factor binding annotations

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