Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy

The ULK complex plays a well-known role in initiating autophagy, to recycle cellular components in response to nutritional stress. Here, the authors demonstrate a late role for ULK in auotophagosome–lysosome fusion and provide a direct link between macroautophagy and chaperone mediated autophagy.

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Autores principales: Chenyao Wang, Huafei Wang, Deyi Zhang, Wenwen Luo, Ruilong Liu, Daqian Xu, Lei Diao, Lujian Liao, Zhixue Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/62852709b9784c59a2fbefdf94a827c2
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