CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing

CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing

Rasmussen Encephalitis is a rare neurological disease accompanied by inflammation and T cell infiltration in the brain. Here the authors show that the severity of this disease correlates with clonal CD8 T cell expansion.

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Autores principales: Tilman Schneider-Hohendorf, Hema Mohan, Christian G. Bien, Johanna Breuer, Albert Becker, Dennis Görlich, Tanja Kuhlmann, Guido Widman, Sebastian Herich, Christiane Elpers, Nico Melzer, Klaus Dornmair, Gerhard Kurlemann, Heinz Wiendl, Nicholas Schwab
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/628a86018f024cc3bd4d4ee72d33b5f0
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https://doaj.org/article/628a86018f024cc3bd4d4ee72d33b5f0

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