CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing

Rasmussen Encephalitis is a rare neurological disease accompanied by inflammation and T cell infiltration in the brain. Here the authors show that the severity of this disease correlates with clonal CD8 T cell expansion.

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Autores principales:	Tilman Schneider-Hohendorf, Hema Mohan, Christian G. Bien, Johanna Breuer, Albert Becker, Dennis Görlich, Tanja Kuhlmann, Guido Widman, Sebastian Herich, Christiane Elpers, Nico Melzer, Klaus Dornmair, Gerhard Kurlemann, Heinz Wiendl, Nicholas Schwab
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/628a86018f024cc3bd4d4ee72d33b5f0
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spelling	oai:doaj.org-article:628a86018f024cc3bd4d4ee72d33b5f02021-12-02T14:39:55ZCD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing10.1038/ncomms111532041-1723https://doaj.org/article/628a86018f024cc3bd4d4ee72d33b5f02016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11153https://doaj.org/toc/2041-1723Rasmussen Encephalitis is a rare neurological disease accompanied by inflammation and T cell infiltration in the brain. Here the authors show that the severity of this disease correlates with clonal CD8 T cell expansion.Tilman Schneider-HohendorfHema MohanChristian G. BienJohanna BreuerAlbert BeckerDennis GörlichTanja KuhlmannGuido WidmanSebastian HerichChristiane ElpersNico MelzerKlaus DornmairGerhard KurlemannHeinz WiendlNicholas SchwabNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tilman Schneider-Hohendorf Hema Mohan Christian G. Bien Johanna Breuer Albert Becker Dennis Görlich Tanja Kuhlmann Guido Widman Sebastian Herich Christiane Elpers Nico Melzer Klaus Dornmair Gerhard Kurlemann Heinz Wiendl Nicholas Schwab CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing
description	Rasmussen Encephalitis is a rare neurological disease accompanied by inflammation and T cell infiltration in the brain. Here the authors show that the severity of this disease correlates with clonal CD8 T cell expansion.
format	article
author	Tilman Schneider-Hohendorf Hema Mohan Christian G. Bien Johanna Breuer Albert Becker Dennis Görlich Tanja Kuhlmann Guido Widman Sebastian Herich Christiane Elpers Nico Melzer Klaus Dornmair Gerhard Kurlemann Heinz Wiendl Nicholas Schwab
author_facet	Tilman Schneider-Hohendorf Hema Mohan Christian G. Bien Johanna Breuer Albert Becker Dennis Görlich Tanja Kuhlmann Guido Widman Sebastian Herich Christiane Elpers Nico Melzer Klaus Dornmair Gerhard Kurlemann Heinz Wiendl Nicholas Schwab
author_sort	Tilman Schneider-Hohendorf
title	CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing
title_short	CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing
title_full	CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing
title_fullStr	CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing
title_full_unstemmed	CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing
title_sort	cd8+ t-cell pathogenicity in rasmussen encephalitis elucidated by large-scale t-cell receptor sequencing
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/628a86018f024cc3bd4d4ee72d33b5f0
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CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing

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