Nickel-catalysed retro-hydroamidocarbonylation of aliphatic amides to olefins

Converting the normally highly stable amide bond into different functionalities is a challenging task. Here the authors report a nickel-catalysed retro-hydroamidocarbonylation procedure, allowing the conversion of aliphatic amides into alkenes across a range of substrates.

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Bibliographic Details
Main Authors: Jiefeng Hu, Minyan Wang, Xinghui Pu, Zhuangzhi Shi
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/629ee0cf137647e4abfb992fc7af714d
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Summary:Converting the normally highly stable amide bond into different functionalities is a challenging task. Here the authors report a nickel-catalysed retro-hydroamidocarbonylation procedure, allowing the conversion of aliphatic amides into alkenes across a range of substrates.