Deep and clear optical imaging of thick inhomogeneous samples.

Inhomogeneity in thick biological specimens results in poor imaging by light microscopy, which deteriorates as the focal plane moves deeper into the specimen. Here, we have combined selective plane illumination microscopy (SPIM) with wavefront sensor adaptive optics (wao). Our waoSPIM is based on a...

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Autores principales: Raphael Jorand, Gwénaële Le Corre, Jordi Andilla, Amina Maandhui, Céline Frongia, Valérie Lobjois, Bernard Ducommun, Corinne Lorenzo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/629f34a6720b44a7bc26b06e91918903
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