A Highly Potent Class of Halogenated Phenazine Antibacterial and Biofilm-Eradicating Agents Accessed Through a Modular Wohl-Aue Synthesis
Abstract Unlike individual, free-floating planktonic bacteria, biofilms are surface-attached communities of slow- or non-replicating bacteria encased within a protective extracellular polymeric matrix enabling persistent bacterial populations to tolerate high concentrations of antimicrobials. Our cu...
Saved in:
Main Authors: | Hongfen Yang, Yasmeen Abouelhassan, Gena M. Burch, Dimitris Kallifidas, Guangtao Huang, Hussain Yousaf, Shouguang Jin, Hendrik Luesch, Robert W. Huigens |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/62a3897341ce43c38d6c44317c2f1d98 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Two-dimensional tessellation by molecular tiles constructed from halogen–halogen and halogen–metal networks
by: Fang Cheng, et al.
Published: (2018) -
Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF
by: Christina Diederich, et al.
Published: (2017) -
π covalency in the halogen bond
by: Cameron W. Kellett, et al.
Published: (2020) -
Phenazine production promotes antibiotic tolerance and metabolic heterogeneity in Pseudomonas aeruginosa biofilms
by: Konstanze T. Schiessl, et al.
Published: (2019) -
Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds
by: Anja Kolarič, et al.
Published: (2021)