Neuronal control of peripheral insulin sensitivity and glucose metabolism

The brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to dise...

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Main Authors: Johan Ruud, Sophie M. Steculorum, Jens C. Brüning
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/62a98d37c005424dbfdf3e77a01d017e
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spelling oai:doaj.org-article:62a98d37c005424dbfdf3e77a01d017e2021-12-02T14:40:34ZNeuronal control of peripheral insulin sensitivity and glucose metabolism10.1038/ncomms152592041-1723https://doaj.org/article/62a98d37c005424dbfdf3e77a01d017e2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15259https://doaj.org/toc/2041-1723The brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to disease.Johan RuudSophie M. SteculorumJens C. BrüningNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Johan Ruud
Sophie M. Steculorum
Jens C. Brüning
Neuronal control of peripheral insulin sensitivity and glucose metabolism
description The brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to disease.
format article
author Johan Ruud
Sophie M. Steculorum
Jens C. Brüning
author_facet Johan Ruud
Sophie M. Steculorum
Jens C. Brüning
author_sort Johan Ruud
title Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_short Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_full Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_fullStr Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_full_unstemmed Neuronal control of peripheral insulin sensitivity and glucose metabolism
title_sort neuronal control of peripheral insulin sensitivity and glucose metabolism
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/62a98d37c005424dbfdf3e77a01d017e
work_keys_str_mv AT johanruud neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism
AT sophiemsteculorum neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism
AT jenscbruning neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism
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