Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen
Here, Depledge et al. use nanopore arrays for direct RNA sequencing to profile the HSV-1 transcriptome in productively infected cells. Sequencing of individual RNAs reveals a highly complex viral transcriptome including mRNAs encoding new viral fusion proteins derived by read-through transcription.
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/62e6f7e4a2564e61a8a33f67a99d8972 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|