Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62

Abstract ES-62, a glycoprotein secreted by the parasitic filarial nematode Acanthocheilonema viteae, subverts host immune responses towards anti-inflammatory phenotypes by virtue of covalently attached phosphorylcholine (PC). The PC dictates that ES-62 exhibits protection in murine models of inflamm...

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Autores principales: Felicity E. Lumb, James Doonan, Kara S. Bell, Miguel A. Pineda, Marlene Corbet, Colin J. Suckling, Margaret M. Harnett, William Harnett
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/630b811b03324ca2ba57f8104374c764
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