A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling.
G protein-coupled receptors (GPCRs) allow cells to respond to chemical and sensory stimuli through generation of second messengers, such as cyclic AMP (cAMP), which in turn mediate a myriad of processes, including cell survival, proliferation, and differentiation. In order to gain deeper insights in...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2020
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/630edfde867848fbacb1414356ff24bb |
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