Sodium butyrate inhibits colitis-associated colorectal cancer through preventing the gut microbiota dysbiosis and reducing the expression of NLRP3 and IL-1β

Sodium butyrate inhibits colitis-associated colorectal cancer through preventing the gut microbiota dysbiosis and reducing the expression of NLRP3 and IL-1β

Sodium butyrate (NaB) is a by-product of dietary fiber that has an anti-tumor effect on colorectal cancer (CRC). The aim of this study was to explore the effect of NaB on tumor and colitis using a colitis-associated colorectal cancer (CAC) model. CAC model was induced in mice by administration of az...

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Autores principales: Huahuan Liu, Zhongbo Bian, Qiuyu Zhang, Zhipeng Xiao, Yu Cao, Xiaodie Sun, Yong Qin, Lianzhi Mao, Xinwei Chu, Wenzhen Liao, Longying Zha, Suxia Sun
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Sodium butyrate
AOM/DSS
Gut microbiota
NLRP3
Colorectal cancer
Nutrition. Foods and food supply
TX341-641
Acceso en línea:https://doaj.org/article/631440c24edc4d518822b0b817b1dd07
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https://doaj.org/article/631440c24edc4d518822b0b817b1dd07

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