Sodium butyrate inhibits colitis-associated colorectal cancer through preventing the gut microbiota dysbiosis and reducing the expression of NLRP3 and IL-1β

Sodium butyrate inhibits colitis-associated colorectal cancer through preventing the gut microbiota dysbiosis and reducing the expression of NLRP3 and IL-1β

Sodium butyrate (NaB) is a by-product of dietary fiber that has an anti-tumor effect on colorectal cancer (CRC). The aim of this study was to explore the effect of NaB on tumor and colitis using a colitis-associated colorectal cancer (CAC) model. CAC model was induced in mice by administration of az...

Full description

Saved in:
Bibliographic Details
Main Authors: Huahuan Liu, Zhongbo Bian, Qiuyu Zhang, Zhipeng Xiao, Yu Cao, Xiaodie Sun, Yong Qin, Lianzhi Mao, Xinwei Chu, Wenzhen Liao, Longying Zha, Suxia Sun
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Sodium butyrate
AOM/DSS
Gut microbiota
NLRP3
Colorectal cancer
Nutrition. Foods and food supply
TX341-641
Online Access:https://doaj.org/article/631440c24edc4d518822b0b817b1dd07
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/631440c24edc4d518822b0b817b1dd07

Similar Items