T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

Germline-encoded mycolyl lipid-reactive (GEM) T cells recognize CD1b proteins presenting mycobacterial mycolates via their T-cell receptors (TCRs). Here, the authors present the structure of this interaction and provide a molecular basis for the co-recognition of CD1b and a mycobacterial glycolipid.

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Autores principales:	Stephanie Gras, Ildiko Van Rhijn, Adam Shahine, Tan-Yun Cheng, Mugdha Bhati, Li Lynn Tan, Hanim Halim, Kathryn D. Tuttle, Laurent Gapin, Jérôme Le Nours, D. Branch Moody, Jamie Rossjohn
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6334ebee5b454f54b0c32fa67fdc1261
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spelling	oai:doaj.org-article:6334ebee5b454f54b0c32fa67fdc12612021-12-02T14:39:11ZT cell receptor recognition of CD1b presenting a mycobacterial glycolipid10.1038/ncomms132572041-1723https://doaj.org/article/6334ebee5b454f54b0c32fa67fdc12612016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13257https://doaj.org/toc/2041-1723Germline-encoded mycolyl lipid-reactive (GEM) T cells recognize CD1b proteins presenting mycobacterial mycolates via their T-cell receptors (TCRs). Here, the authors present the structure of this interaction and provide a molecular basis for the co-recognition of CD1b and a mycobacterial glycolipid.Stephanie GrasIldiko Van RhijnAdam ShahineTan-Yun ChengMugdha BhatiLi Lynn TanHanim HalimKathryn D. TuttleLaurent GapinJérôme Le NoursD. Branch MoodyJamie RossjohnNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stephanie Gras Ildiko Van Rhijn Adam Shahine Tan-Yun Cheng Mugdha Bhati Li Lynn Tan Hanim Halim Kathryn D. Tuttle Laurent Gapin Jérôme Le Nours D. Branch Moody Jamie Rossjohn T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
description	Germline-encoded mycolyl lipid-reactive (GEM) T cells recognize CD1b proteins presenting mycobacterial mycolates via their T-cell receptors (TCRs). Here, the authors present the structure of this interaction and provide a molecular basis for the co-recognition of CD1b and a mycobacterial glycolipid.
format	article
author	Stephanie Gras Ildiko Van Rhijn Adam Shahine Tan-Yun Cheng Mugdha Bhati Li Lynn Tan Hanim Halim Kathryn D. Tuttle Laurent Gapin Jérôme Le Nours D. Branch Moody Jamie Rossjohn
author_facet	Stephanie Gras Ildiko Van Rhijn Adam Shahine Tan-Yun Cheng Mugdha Bhati Li Lynn Tan Hanim Halim Kathryn D. Tuttle Laurent Gapin Jérôme Le Nours D. Branch Moody Jamie Rossjohn
author_sort	Stephanie Gras
title	T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
title_short	T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
title_full	T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
title_fullStr	T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
title_full_unstemmed	T cell receptor recognition of CD1b presenting a mycobacterial glycolipid
title_sort	t cell receptor recognition of cd1b presenting a mycobacterial glycolipid
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/6334ebee5b454f54b0c32fa67fdc1261
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T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

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