Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

por Kok Fei Chan, Benjamin S. Gully, Stephanie Gras, Dennis X. Beringer, Lars Kjer-Nielsen, Jonathan Cebon, James McCluskey, Weisan Chen, Jamie Rossjohn
Publicado 2018

Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

por Emma J. Grant, Tracy M. Josephs, Liyen Loh, E. Bridie Clemens, Sneha Sant, Mandvi Bharadwaj, Weisan Chen, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska
Publicado 2018

Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition

por Gautham R. Balaji, Oscar A. Aguilar, Miho Tanaka, Miguel A. Shingu-Vazquez, Zhihui Fu, Benjamin S. Gully, Lewis L. Lanier, James R. Carlyle, Jamie Rossjohn, Richard Berry
Publicado 2018

Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.

por Sophie A Valkenburg, Stephanie Gras, Carole Guillonneau, Nicole L La Gruta, Paul G Thomas, Anthony W Purcell, Jamie Rossjohn, Peter C Doherty, Stephen J Turner, Katherine Kedzierska
Publicado 2010

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

por Erin W. Meermeier, Bruno F. Laugel, Andrew K. Sewell, Alexandra J. Corbett, Jamie Rossjohn, James McCluskey, Melanie J. Harriff, Tamera Franks, Marielle C. Gold, David M. Lewinsohn
Publicado 2016

Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells

por Jeffrey Y. W. Mak, Weijun Xu, Robert C. Reid, Alexandra J. Corbett, Bronwyn S. Meehan, Huimeng Wang, Zhenjun Chen, Jamie Rossjohn, James McCluskey, Ligong Liu, David P. Fairlie
Publicado 2017

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

por Stephanie Gras, Ildiko Van Rhijn, Adam Shahine, Tan-Yun Cheng, Mugdha Bhati, Li Lynn Tan, Hanim Halim, Kathryn D. Tuttle, Laurent Gapin, Jérôme Le Nours, D. Branch Moody, Jamie Rossjohn
Publicado 2016

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity

por Amine Toubal, Badr Kiaf, Lucie Beaudoin, Lucie Cagninacci, Moez Rhimi, Blandine Fruchet, Jennifer da Silva, Alexandra J. Corbett, Yannick Simoni, Olivier Lantz, Jamie Rossjohn, James McCluskey, Philippe Lesnik, Emmanuelle Maguin, Agnès Lehuen
Publicado 2020

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

por Adam Shahine, Peter Reinink, Josephine F. Reijneveld, Stephanie Gras, Mira Holzheimer, Tan-Yun Cheng, Adriaan J. Minnaard, John D. Altman, Steffi Lenz, Jacques Prandi, Joanna Kubler-Kielb, D. Branch Moody, Jamie Rossjohn, Ildiko Van Rhijn
Publicado 2019

Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens

por Jérôme Le Nours, T. Praveena, Daniel G. Pellicci, Nicholas A. Gherardin, Fiona J. Ross, Ricky T. Lim, Gurdyal S. Besra, Santosh Keshipeddy, Stewart K. Richardson, Amy R. Howell, Stephanie Gras, Dale I. Godfrey, Jamie Rossjohn, Adam P. Uldrich
Publicado 2016

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

por Catarina F. Almeida, Srinivasan Sundararaj, Jérôme Le Nours, T. Praveena, Benjamin Cao, Satvika Burugupalli, Dylan G. M. Smith, Onisha Patel, Manfred Brigl, Daniel G. Pellicci, Spencer J. Williams, Adam P. Uldrich, Dale I. Godfrey, Jamie Rossjohn
Publicado 2019

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

por Patricia T. Illing, Phillip Pymm, Nathan P. Croft, Hugo G. Hilton, Vladimir Jojic, Alex S. Han, Juan L. Mendoza, Nicole A. Mifsud, Nadine L. Dudek, James McCluskey, Peter Parham, Jamie Rossjohn, Julian P. Vivian, Anthony W. Purcell
Publicado 2018

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8

por Mai T. Tran, Pouya Faridi, Jia Jia Lim, Yi Tian Ting, Goodluck Onwukwe, Pushpak Bhattacharjee, Claerwen M. Jones, Eleonora Tresoldi, Fergus J. Cameron, Nicole L. La Gruta, Anthony W. Purcell, Stuart I. Mannering, Jamie Rossjohn, Hugh H. Reid
Publicado 2021

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C

por Shoeib Moradi, Sanda Stankovic, Geraldine M. O’Connor, Phillip Pymm, Bruce J. MacLachlan, Camilla Faoro, Christelle Retière, Lucy C. Sullivan, Philippa M. Saunders, Jacqueline Widjaja, Shea Cox-Livingstone, Jamie Rossjohn, Andrew G. Brooks, Julian P. Vivian
Publicado 2021

Structural and regulatory diversity shape HLA-C protein expression levels

por Gurman Kaur, Stephanie Gras, Jesse I. Mobbs, Julian P. Vivian, Adrian Cortes, Thomas Barber, Subita Balaram Kuttikkatte, Lise Torp Jensen, Kathrine E. Attfield, Calliope A. Dendrou, Mary Carrington, Gil McVean, Anthony W. Purcell, Jamie Rossjohn, Lars Fugger
Publicado 2017

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

por Joshua D. Ooi, Jhih-Hang Jiang, Peter J. Eggenhuizen, Ling L. Chua, Mirjan van Timmeren, Khai L. Loh, Kim M. O’Sullivan, Poh Y. Gan, Yong Zhong, Kirill Tsyganov, Lani R. Shochet, Jessica Ryan, Coen A. Stegeman, Lars Fugger, Hugh H. Reid, Jamie Rossjohn, Peter Heeringa, Stephen R. Holdsworth, Anton Y. Peleg, A. Richard Kitching
Publicado 2019

Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection

por Zhe Zhao, Huimeng Wang, Mai Shi, Tianyuan Zhu, Troi Pediongco, Xin Yi Lim, Bronwyn S. Meehan, Adam G. Nelson, David P. Fairlie, Jeffrey Y. W. Mak, Sidonia B. G. Eckle, Marcela de Lima Moreira, Carolin Tumpach, Michael Bramhall, Cameron G. Williams, Hyun Jae Lee, Ashraful Haque, Maximilien Evrard, Jamie Rossjohn, James McCluskey, Alexandra J. Corbett, Zhenjun Chen
Publicado 2021

MAIT cells protect against pulmonary Legionella longbeachae infection

por Huimeng Wang, Criselle D’Souza, Xin Yi Lim, Lyudmila Kostenko, Troi J. Pediongco, Sidonia B. G. Eckle, Bronwyn S. Meehan, Mai Shi, Nancy Wang, Shihan Li, Ligong Liu, Jeffrey Y. W. Mak, David P. Fairlie, Yoichiro Iwakura, Jennifer M. Gunnersen, Andrew W. Stent, Dale I. Godfrey, Jamie Rossjohn, Glen P. Westall, Lars Kjer-Nielsen, Richard A. Strugnell, James McCluskey, Alexandra J. Corbett, Timothy S. C. Hinks, Zhenjun Chen
Publicado 2018

Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients

por Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Jeremy Chase Crawford, Liyen Loh, Sneha Sant, Ludivine Grzelak, Emma K. Allen, Tim Brahm, E. Bridie Clemens, Maria Auladell, Luca Hensen, Zhongfang Wang, Simone Nüssing, Xiaoxiao Jia, Patrick Günther, Adam K. Wheatley, Stephen J. Kent, Malet Aban, Yi-Mo Deng, Karen L. Laurie, Aeron C. Hurt, Stephanie Gras, Jamie Rossjohn, Jane Crowe, Jianqing Xu, David Jackson, Lorena E. Brown, Nicole La Gruta, Weisan Chen, Peter C. Doherty, Stephen J. Turner, Tom C. Kotsimbos, Paul G. Thomas, Allen C. Cheng, Katherine Kedzierska
Publicado 2021

CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

por Luca Hensen, Patricia T. Illing, E. Bridie Clemens, Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Nicole A. Mifsud, Andrea T. Nguyen, Christopher Szeto, Brendon Y. Chua, Hanim Halim, Simone Rizzetto, Fabio Luciani, Liyen Loh, Emma J. Grant, Phillipa M. Saunders, Andrew G. Brooks, Steve Rockman, Tom C. Kotsimbos, Allen C. Cheng, Michael Richards, Glen P. Westall, Linda M. Wakim, Thomas Loudovaris, Stuart I. Mannering, Michael Elliott, Stuart G. Tangye, David C. Jackson, Katie L. Flanagan, Jamie Rossjohn, Stephanie Gras, Jane Davies, Adrian Miller, Steven Y. C. Tong, Anthony W. Purcell, Katherine Kedzierska
Publicado 2021