Modeling Site-Specific Nucleotide Biases Affecting Himar1 Transposon Insertion Frequencies in TnSeq Data Sets
When using the Himar1 transposon to create transposon insertion mutant libraries, it is known that the transposon is restricted to insertions at TA dinucleotide sites throughout the genome, and the absence of insertions is used to infer which genes are essential (or conditionally essential) in a ba...
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| Main Authors: | , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/639d8bc4ff574b599af7ecfa2b2035f1 |
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