Regulation of innate immune responses in macrophages differentiated in the presence of vitamin D and infected with dengue virus 2.

A dysregulated or exacerbated inflammatory response is thought to be the key driver of the pathogenesis of severe disease caused by the mosquito-borne dengue virus (DENV). Compounds that restrict virus replication and modulate the inflammatory response could thus serve as promising therapeutics miti...

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Auteurs principaux: Jorge Andrés Castillo, Diana M Giraldo, Juan C Hernandez, Jolanda M Smit, Izabela A Rodenhuis-Zybert, Silvio Urcuqui-Inchima
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/63db230099ec4adf8a56a23c23246927
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