Flavin-dependent halogenases catalyze enantioselective olefin halocyclization
Catalytic enantioselective halocyclization of alkenes is an important bond forming tool and a key step in natural product biosynthesis, but so far no examples of the enzymatic counterpart of this reaction on simple achiral olefins have been reported. Here, the authors describe examples of engineered...
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Autores principales: | Dibyendu Mondal, Brian F. Fisher, Yuhua Jiang, Jared C. Lewis |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/63f27c4868c346a9a24685a83de202f3 |
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