Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment
Abstract To better understand the full-length transcriptome of the nucleus accumbens (NAc)—a key brain reward region—in chronic cocaine treatment, we perform the first single molecule, long-read sequencing analysis using the Iso-seq method to detect 42,114 unique transcripts from mouse NAc polyadeny...
Enregistré dans:
Auteurs principaux: | Molly Estill, Efrain Ribeiro, Nancy J. Francoeur, Melissa L. Smith, Robert Sebra, Szu-Ying Yeh, Ashley M. Cunningham, Eric J. Nestler, Li Shen |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/63fe549b0c524dd38ff824a5f1b22884 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine
par: Efrain A. Ribeiro, et autres
Publié: (2018) -
Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens
par: Alberto J. López, et autres
Publié: (2021) -
AMPK signaling in the nucleus accumbens core mediates cue-induced reinstatement of cocaine seeking
par: Xue-Jiao Gao, et autres
Publié: (2017) -
BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens
par: André O. White, et autres
Publié: (2016) -
Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats
par: Marsida Kallupi, et autres
Publié: (2022)